Surgical Bone Substitute
& Regeneration

Kervalion,
a key player in the future biomaterials biomaterials dental

KERVALION develops 3D-printed bone grafts, custom-designed from patient scans.

Initially intended for pre-implant dental surgery, these grafts are designed to treat bone deficits that prevent the placement of dental implants. Thanks to customized manufacturing, they adapt perfectly in shape and volume, simplifying surgery and reducing the number of surgical procedures required. KERVALION's innovative material guarantees excellent tolerance, while promoting reliable bone regeneration.

This technology offers practitioners an easier, faster and more cost-effective solution, making grafting accessible to a greater number of professionals, while improving patient comfort.

A public health issue

Permanent tooth decay affects over 2 billion people worldwide, and every year 2 million dental implants are placed in Europe.

However, up to 50% of dental implant procedures require bone filling due to insufficient bone volume.

Bone reconstruction in pre-implant surgery: known limitations

Current bone reconstruction methods include:
- Autografting, considered the "gold standard"
- Allografts (of human, animal or synthetic origin)
However, these techniques have a number of drawbacks:
- They require the intervention of specialized surgeons
- They involve several operations (3 to 4 on average)
- They require a long treatment time (6 to 12 months)
- They generate significant costs (up to €1,500)
- They carry a risk of infection
- They have a significant failure rate (10 to 20%)

These limitations call for a more rapid, efficient and accessible approach to meet the growing needs of patients and professionals alike.

Kervalion innovation in dental bone reconstruction

KERVALION offers a novel, ready-to-use solution for the treatment of patients suffering from dental bone resorption. Thanks to 3D printing, we can design personalized bone substitutes, tailored to each individual patient. KERVALION uses 3D printing to shape the biomaterial, enabling unrivalled precision in graft manufacture. This advanced technique guarantees a bone graft with optimal biological and mechanical properties, essential for graft success. This innovative approach promises to revolutionize the field of pre-implant surgery, offering a tailor-made, effective and less invasive solution for patients requiring bone reconstruction prior to the placement of dental implants.

The key benefits of our innovation :

Personalization made-to-measure :

The graft is designed from a CT scan for perfect morphological adaptation, optimizing integration and results.

Properties antibacterial :

KERVALION material incorporates an antibacterial treatment, reducing the risk of post-operative infection and promoting better healing.

A single surgical surgical procedure :

The technology makes it possible to reduce the procedure to a single surgical act, considerably reducing treatment time and inconvenience for the patient.

Performance biomechanical :

KERVALION
bone substitute offers biological and mechanical properties equivalent or superior to existing solutions, ensuring effective and efficient bone regeneration.

The global market for dental bone graft substitutes

The global market for dental bone grafts is growing significantly, with a compound annual growth rate (CAGR) of between 6.8% and 9.2%, reflecting the increasing importance of bone reconstruction procedures in the dental field.

In Europe :

703,420 dental bone grafting procedures were carried out in the main countries (Germany, France, Italy, Spain, England), underlining the substantial demand on the continent.

United States:

the market is particularly dynamic, with 1,651,091 procedures carried out, making it the world leader in this field. This strong demand is due to an advanced healthcare infrastructure and increased awareness
of oral health
.

Emerging markets :

they also show considerable potential. Brazil, Russia, India and China collectively performed 1,285,033 procedures, indicating a growing adoption of dental bone grafting techniques in these regions.

One notable trend is the expected growth of the synthetic graft market, which is expected to post the strongest growth between now and 2030.

The global market for dental bone grafts is experiencing significant growth, driven by increased demand for dental implants and technological advances.

The global market for dental bone grafts is growing significantly, with a compound annual growth rate (CAGR) of between 6.8% and 9.2%, reflecting the increasing importance of bone reconstruction procedures in the dental field.

Roadmap

The team

Habib BELAID

Co-founder & CEO

Fanny BARRANGER

Materials Chemistry Engineer

Aurélien BON

3D Design Engineer

Marilyn Kajdan

Biological engineer

Mikhael BECHELANY

Co-founder & Materials Research Manager

David CORNU

Co-founder & University Professor of Materials

Vincent CAVAILLES

Co-founder & Director of Biology Research

Gilles Devillers

Co-founder & Managing Director
Chief Business Officer

Our social and environmental commitments

KERVALION is committed to providing innovative medical solutions while minimizing its environmental impact, demonstrating
that it is possible to combine medical progress and ecological responsibility.

A strong social impact

KERVALION is committed to providing innovative medical solutions while minimizing its environmental impact, demonstrating
that it is possible to combine medical progress and ecological responsibility.

Local production and made in France: we work with local suppliers and service providers to promote the national economy while reducing our carbon footprint. Controlled 3D printing: manufacturing unique parts with optimized resources and reduced waste.
Biobased raw materials: materials that respect the environment and health, limiting the use of human bone banks
.
Optimized logistics: reducing the number and duration of transports.

An eco-responsible model

Partners

Contact

CAP ALPHA
3 av. de l'europe - 34830 Clapiers
France
Tel: 06 88 45 78 86
E-Mail: contact@kervalion.com