Surgical Bone Substitute
& Regeneration

Kervalion,
a key player in the future of biomaterials in dental implantology

KERVALION develops 3D-printed bone grafts, custom-designed from patient scans.

Initially intended for dental pre-implant surgery, these grafts aim to address bone deficiencies that preclude the placement of dental implants. Thanks to personalized manufacturing, they achieve a perfect fit in both shape and volume, simplifying the procedure and reducing the number of surgical interventions required. KERVALION's innovative material ensures excellent tolerance while promoting reliable bone regeneration.

This technology offers practitioners an easier, faster, and more cost-effective solution, thereby making bone grafting accessible to a wider range of professionals, while simultaneously enhancing patient comfort.

A Public Health Challenge

Dental caries in permanent teeth affect over 2 billion people worldwide, and annually, 2 million dental implants are placed in Europe.

However, up to 50% of dental implant procedures require bone augmentation due to insufficient bone volume.

Bone Reconstruction in Pre-Implant Surgery: Known Limitations

Currently, bone reconstruction methods include:
– Autografts, considered the « gold standard »
– Allografts (of human, animal, or synthetic origin)
However, these techniques present several disadvantages:
– They require intervention by specialized surgeons
– They involve multiple operations (3 to 4 on average)
– They necessitate a long treatment time (6 to 12 months)
– They incur significant costs (up to €1,500)
– They carry a risk of infection
– They exhibit a non-negligible failure rate (10 to 20%)

These limitations necessitate a faster, more effective, and accessible approach to meet the growing needs of both patients and professionals.

Kervalion's Innovation in Dental Bone Reconstruction

KERVALION offers a novel, ready-to-use solution for treating patients suffering from dental bone resorption. Utilizing 3D printing, we design personalized bone substitutes tailored for each patient. KERVALION employs 3D printing to shape the biomaterial, enabling unparalleled precision in graft fabrication. This advanced technique ensures the production of a bone graft with optimal biological and mechanical properties, which are crucial for successful grafting. This innovative approach promises to revolutionize the field of pre-implant surgery by providing a customized, effective, and less invasive solution for patients requiring bone reconstruction prior to dental implant placement.

Key Advantages of Our Innovation:

Tailored Customization:

The graft is designed from a scan to ensure perfect morphological adaptation, thereby optimizing integration and outcomes.

Single Surgical Procedure:

This technology allows for reducing the intervention to a single surgical procedure, significantly decreasing treatment time and patient discomfort.

Biomechanical Performance:

The KERVALION bone substitute
offers biological and mechanical properties equivalent or superior to existing solutions, ensuring effective and efficient bone regeneration.

The Global Market for Dental Bone Graft Substitutes

The global dental bone graft market is experiencing significant growth, with a compound annual growth rate (CAGR) between 6.8% and 9.2%, reflecting the increasing importance of bone reconstruction procedures in the dental field.

In Europe:

703,420 dental bone graft procedures were performed in key countries (Germany, France, Italy, Spain, England), underscoring substantial demand across the continent.

In the United States:

The market is particularly dynamic, with 1,651,091 procedures performed, positioning it as the global leader in this field. This robust demand is attributed to an advanced healthcare infrastructure and heightened awareness
of oral and
dental health.

Emerging Markets:

They also demonstrate considerable potential. Brazil, Russia, India, and China collectively performed 1,285,033 procedures, indicating a growing adoption of dental bone grafting techniques in these regions.

A notable trend is the anticipated growth of the synthetic graft market, which is projected to show the strongest progression by 2030.

The global dental bone graft market is experiencing significant growth, driven by increased demand for dental implants and technological advancements.

The global dental bone graft market is experiencing substantial growth, with a Compound Annual Growth Rate (CAGR) projected between 6.8% and 9.2%, reflecting the increasing significance of bone reconstruction procedures in the dental field.

Roadmap

The Team

Habib BELAID

Co-founder & CEO

Fanny BARRANGER

Materials Chemistry Engineer

Aurélien BON

3D Design Engineer

Marilyn Kajdan

Biological Engineer

Mikhael BECHELANY

Co-founder & Materials Research Director

David CORNU

Co-founder & University Professor, Materials

Vincent CAVAILLES

Co-founder & Research Director, Biology

Gilles Devillers

Co-founder & General Manager
Chief Business Officer

Our Social and Environmental Commitments

KERVALION is committed to providing innovative medical solutions while minimizing its environmental impact, demonstrating
that medical advancement and ecological responsibility can be harmonized.

Significant Social Impact

KERVALION is committed to providing innovative medical solutions while minimizing its environmental impact, demonstrating
that medical advancement and ecological responsibility can be harmonized.

Local Production and Made in France: We collaborate with local suppliers and service providers to foster the national economy while reducing our carbon footprint. Controlled 3D Printing: manufacturing unique components with optimized resource utilization and reduced waste.
Biosourced Raw Materials: Environmentally and health-friendly materials, limiting the reliance on human bone banks.
.
Optimized Logistics: Reducing the volume and duration of transportation.

A Sustainable Model

Partners

Contacts

CAP ALPHA
3 Avenue de l'Europe – 34830 Clapiers
France
Tel: 06 88 45 78 86
E-Mail: contact@kervalion.com